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Personalized formulas
All treatments Acne Acne scars & pigmentation Aging Hyperpigmentation Melasma Skin glow Rosacea
Routine essentials
All Products Clarifying Azelaic Acid 15–20% Cream The Balancing Kit SAVE The Nourishing Kit SAVE Balancing Glycerin Gel Cleanser Caring Squalane Cream Cleanser Hydrating Hyaluronic Acid + Vit B5 Serum Soothing Centella Gel Moisturizer Nourishing Ceramide + Peptide Moisturizer Restoring Ceramide Skin Balm Blemish Control Kit Brightening & Barrier Repair Kit
Dermatica products
Your skincare, solved
Your skincare should be anything but routine, and these derm-approved products are developed to achieve your skin’s incredible potential.
View Clarifying Azelaic Acid 15–20% Cream Page
Fade the appearance of dark spots for a brighter, more even skin tone with this multi-tasking cream.
View The Balancing Kit Page
Your complete starter kit for blemish and breakout-prone skin.
View The Nourishing Kit Page
Your complete starter kit for glowing, healthy skin.
View Balancing Glycerin Gel Cleanser Page
Rebalance oily, blemish-prone skin with a gentle makeup-removing cleanser.
View Caring Squalane Cream Cleanser Page
Nourish balanced or dry skin with a makeup-removing, cream-to-oil-to-milk cleanser.
View Hydrating Hyaluronic Acid + Vit B5 Serum Page
Give dry, oily or combination skin a hydrating boost with moisture-locking vitamin B5 and smoothing hyaluronic acid.
View Soothing Centella Gel Moisturizer Page
Protect and hydrate oily and combination skin with this lightweight oil-free gel moisturizer.
View Nourishing Ceramide + Peptide Moisturizer Page
Effective hydration for balanced or dry skin with moisture-locking niacinamide and soothing ceramides.
View Restoring Ceramide Skin Balm Page
Speed up retinization recovery with a targeted barrier balm for dry, irritated or flaky skin.
View Blemish Control Kit Page
Your daily routine for blemish-prone skin.
View Brightening & Barrier Repair Kit Page
Your radiance-boosting daily routine for glowing, resilient skin.
acne
Prescription treatments made for you
Breakouts. Pigmentation. Wrinkles - we have you covered. The best ingredients for healthy skin tailored to yours needs.
acne
Prescription acne treatments
Treat and clear spots, pimples, whiteheads, blackheads, breakouts, blemishes and cystic acne.
acne-scars
Prescription treatments for acne scars & pigmentation
Reduce red or dark marks from acne, and smooth the skin’s texture.
anti-ageing
Prescription anti-aging treatments
Reduce wrinkles, improve pigmentation, skin texture and smoothness.
hyperpigmentation
Prescription hyperpigmentation treatments
Reduce the appearance of wrinkles, scars marks, dark spots and hyper-pigmentation.
melasma
Prescription melasma treatments
Reduce pigmentation from melasma to improve and even out your skin tone.
vitality
Prescription skin glow treatments
Achieve healthy-looking and radiant skin.
rosacea
Prescription rosacea treatments
Reduce and control redness or flare-ups and protect sensitive skin.
Adapalene Benzoyl peroxide Tretinoin
Other ingredients
Clindamycin, hydroquinone, ivermectin, metronidazole, niacinamide
ingredients
Evidence-based ingredients
Our formulas are made with effective science-backed actives that are gentle on your skin.
How it works Pricing Meet the team Support centre Our mission Read our blog Affiliates
Dermatica - Smiling woman holding Dermatica bottle in the hand

The next generation of anti-aging prescription skincare

Get a personalized formula with active ingredients to reduce wrinkles, smooth fine lines and fade dark spots, with visible results within 12 weeks.

Start your free trial

Just pay a $4.99 prescribing fee.

Aging skin worries? A thing of the past

Dull skin
Fine line and wrinkles
Skin firmness
Pigmentation

Aging skin worries? A thing of the past

Why does our skin age?

Everyone’s skin changes as we get older. Collagen production slows down, and factors like sun exposure, pollution and smoking will cause aging too. Visibly, we’ll notice fine lines, wrinkles, pigmentation, more noticeable pores and less elasticity.

Results you’ll love -
here’s the proof

Start your free trial

Just pay a $4.99 prescribing fee.

Dermatica - Check In With Your Dermatology Team Screen View

What’s included?

  1. Powerful personalized formula
  2. Evidence-based ingredients
  3. Up to 20x stronger than the high street
  4. Dashboard to track your progress
  5. Unlimited treatment adjustments
Start your free trial
Discount Tag Illustration Just pay a $4.99 prescribing fee.

Evidence-backed active ingredients

Your formula has precisely measured prescription ingredients to slow and reverse visible signs of aging – and suit your skin.

View all ingredients

The SmartBase

Your personalized formula is supercharged with powerful prescription ingredients and blended with our hydrating SmartBase cream, which contains hyaluronic acid, ceramides, glycerin and panthenol for best results.

Explore our ingredients
Locks in moisture and softens illustration

Locks in moisture and softens

Nourishes your epidermis on multiple levels illustration

Nourishes your epidermis on multiple levels

Strengthens your skin barrier illustration

Strengthens your skin barrier

How it works

  1. reaching goal illustration

    Step 01

    Complete an online consultation

    This will help our dermatology experts prescribe the right formula for your skin

  2. designing treatment plan illustration

    Step 02

    Apply your formula once a night

    With the perfect combination of active ingredients for your unique skin.

  3. adapting treatment formula illustration

    Step 03

    Check in throughout your journey

    We’ll monitor your progress and adjust your treatment as needed.

Start your free trial

Just pay a $4.99 prescribing fee.

Dermatology, designed for you

Dermatology designed for you
  • A personalized formula, developed by experts

    You’ll get a personalized, evidence-based prescription treatment, tailored to your treatment goals.

  • Delivered to you every 56 days (approx.)

    Your bespoke plan arrives with two bottles every 56 days (approximately), and adapts to your skin’s progress.

  • 24/7 support

    You’ll have free, unlimited access to dermatology experts, whenever you need.

  • You’re in total control

    You can pause, reschedule or cancel your plan online. No strings attached.

First month $4.99

then $29.95/month

Start your free trial

Support your treatment with our routine essentials

Our range of daily essentials were designed by dermatologists to work alongside active ingredients. Fragrance free, gentle and effective for all skin types.

Read what others say, in their own words

Showing our favorite reviews
“I love the personalized service & for a great price. I have been really impressed with the product - my skin looks great. It was easy to do the consultation & the retinol cream has been a pleasure to use. It started on a lower % of 0.25 & is now 0.5. Fantastic.”
Sara Caistor
Verified Facebook review ↗
“Amazing service. Brilliant product that I used to pay hundreds of pounds for and amazing results. Tailored to my own skin problems and I can’t recommend Dermatica enough. Easy to cancel if you’re not happy but I guarantee you will be so pleased with the results you will carry on just as I have 😊😊”
Claire Smith
Verified Google review ↗
“Having tried many products before to help with my skin I can honestly say that I have been very impressed with Dermatica...my skin is probably the best it has been in years. Getting the formula was simple enough and the results speak for themselves. Worth every penny.”
Erin Beale
Verified Facebook review ↗
“My skin has been the best it's ever been since I was a teenager my pigmentation has significantly cleared and acne has been kept at bay. I will never use anything other than dermatica I am so relieved I found this brand and have recommended to others. I receive compliments on how good my skin looks it's taken years off me.”
Maria
Verified Reviews.io review ↗
“I am such a fan of Dermatica and their service. Very easy to manage your subscription but as someone with incredibly problematic skin (who last week got complimented by a stranger on it!) I wouldn't be without it. I truly believe prescription skincare offers so much more than all the creams and lotions you can buy OTC.”
TheOGCCL
Verified Mumsnet review ↗
“I’ve been using Tretinoin for almost three months now, and I’m loving it. Great customer service, great results and I’m now up to my maximum dose. I’m definitely seeing some peeling, but nothing that wasn’t explained in the literature you receive with the product. It’s saved me an absolute fortune on skincare, as I used to buy every new product on the market that promised the earth and delivered nothing.”
Sarah Blackley
Verified Facebook review ↗
“The initial process of having the assessment and getting my personalized formula was so fast. Shortly after I received my products which I love so much and it has only been 2 weeks. My major skin concern was uneven dull skin tone, enlarged pores and fine lines. My skin is so glowing like it has never been before! It just looks so healthy and feels so soft. I had a few acne marks which are now faded.”
Réka Bódi
Verified Facebook review ↗
“Dermatica has completely revolutionised my skin care. I am now 63 but my skin has never looked so good or been so healthy. My monthly delivery has become a part of my life now and I will continue for as long as I am able. The service is also second to none. Any questions I've submitted have always been answered promptly and without fuss. I would highly recommend Dermatica to anyone who cares about looking their best for as long as possible.”
Catherine
Verified Reviews.io review ↗
“I have PCOS and have struggled with acne for over 10 years, and have tried what feels like every acne medication available. My skin has never been better than while using my personalized Dermatica treatment, and I'm so happy! The subscription service is also very convenient, so I never have to worry about running out or having to go to the pharmacy for it.”
Bella Duncan
Verified Facebook review ↗
“Love Dermatica. My skin is bright and the large pores and blackheads on my nose have gone. I've been using it for 6 months with Dermatica controlling the strength of the creams supplied to suit. I must say it has saved me a fortune on buying stuff to try and it not working and I can now use basic cleanser and moisturiser.”
Blossomgate22
Verified Mumsnet review ↗
Read more reviews
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4.7/5  |  317 reviews
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4.9/5  |  784 reviews
Dr Catriona Maybury, Consultant Dermatologist
“We use active ingredients that reverse photodamage, soften fine lines, stimulate collagen production and improve skin texture. We create personalized formulas to work for all ages.”
Dr Catriona Maybury, Consultant Dermatologist
Start your free trial

Just pay a $4.99 prescribing fee.

Anti-aging FAQs

What is the difference between tretinoin and retinol?
Retinol, though similar in name, is actually weaker in strength than a retinoid. Both are derived from Vitamin A, but because retinols have a lower concentration than retinoids and are in a different form, it can take longer to see results. Retinols are readily available over the counter, whereas retinoids aren’t available over the counter. At Dermatica, we’re able to provide higher strength topical retinoids that aren’t available over the counter.
What's the best strength of tretinoin for anti-aging?
This depends on your skin type and your tolerance to tretinoin, so it will vary from person-to-person. To make sure your formula is right for your skin, we start patients at a low dose and increase gradually to avoid irritation. If you’ve previously been using a retinoid, you can let us know what strength and we’ll make sure your Dermatica treatment is working at its most effective level.
Can tretinoin improve deep lines such as naso-labial folds, elevens or marionette lines?
The appearance of deeper lines in our face can lessen or fade over time with treatment, however the results may take longer to see than with finer lines. As we age, our body produces less collagen and we can expect to lose some volume (plumpness) in our faces. While tretinoin is known to cause an increase in dermal collagen production, please note that topical treatment alone may not be enough to achieve your desired results with deeper lines. As aging is a continual process, the goal of topical treatment is often to prevent rather than reverse signs of aging.
Will my treatment help with wrinkles?
If your skin goal is to fade the appearance of fine lines and wrinkles, then we’ll carefully select powerful, science-backed active ingredients that should help smooth your skin and give you a more youthful look.

Retinoids are prescribed in Dermatica’s personalized formulas to restore dermal collagen, which improves fine lines. Niacinamide is often added as well to boost ceramide production, which increases hydration levels in your skin.

The ingredients in your formula are chosen by dermatology experts, and the strength will be adjusted as you continue your journey so you can get the best results. For deeper or larger wrinkles, while our active ingredients may improve the texture and appearance, you may need further treatment like fillers or Botulinum Toxin (botox) to fade them completely.

Get industry-leading advice from skin experts

Woman before after
Skin Journeys

Anti-Aging Skin Journey: Carole, 63, Glasgow

Read article
Woman applying tretinoin
Dermatica 101

Where to Apply Tretinoin

Read article
Woman with towel applying treatment
Ask our Derm

How Do I Know My Anti-Aging Treatment is Working?

Read article
Woman with pigmentation
Dermatica 101

Retinoids: Why Skin Purges And How Long It Lasts

Read article
Woman applying botox
Ask our Derm

Ask a Derm: Can I Use Botox® Alongside Tretinoin?

Read article
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